Senior Program Manager (SPM) - Mastocytosis
Sanofi Cambridge, MA Posted 14 July 2026
Pharma
Job description
Job title: Senior Program Manager - Mastocytosis Location: Cambridge, MA About the Job The Senior Program Manager (SPM) will drive business-related initiatives within the Mastocytosis Therapeutic Area (TA), serving as a key operational partner to the Medical Program Lead (MPL) and the Mastocytosis Global Medical Team (GMT). Working collaboratively with internal stakeholders and external Alliance partners (where applicable), the SPM will ensure seamless execution of lifecycle management (LCM) initiatives, launch deliverables, and strategic programs aligned with product development stages. Operating within a dynamic matrix environment, the SPM will coordinate cross-functional resources and activities to deliver on priorities outlined in the Global Medical Plans, ensuring strategic alignment and operational excellence across all TA-specific initiatives. Join the engine of Sanofi's mission — where deep immuno-science meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions. About Sanofi: We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives. Main Responsibilities: Strategic Partnership & Leadership • Lead program management initiatives for Mastocytosis in strategic partnership with the Medical Program Lead (MPL) • Collaborate with Global Medical Director to operationalize Global Medical Team strategies and deliverables • Drive integrated evidence generation planning through cross-functional partnerships with Global Medical Directors, Brand teams, and functional leads Study Lifecycle & Portfolio Management • Oversee comprehensive study lifecycle management, including process optimization, timeline coordination, and budget oversight for: Company-Sponsored Studies (CSS): Manage approval process and serve as central Medical liaison for Clinical Sciences and Operations (CSO) communications and partnerships Investigator-Sponsored Studies (ISS) & Real-World Evidence (RWE): Partner with key stakeholders to capture operational details, study milestones, and budget requirements aligned with Medical plans Compliance & Reporting: Ensure adherence to study compliance requirements Operational Excellence & Process Management • Optimize cross-functional communication and decision-making through meeting facilitation and stakeholder engagement • Streamline operational workflows to ensure compliance with internal SOPs and external regulatory guidelines • Utilize harmonized Program Management Tools to manage portfolio-level activities across the Program Management organization Stakeholder & Alliance Partner Engagement • Build and maintain strategic partnerships with internal teams and external collaborators • Serve as primary advocate for alliance partner relationships (where applicable), ensuring alignment with collaboration objectives and deliverables • Provide specialized program management support for Therapeutic Area-specific initiatives and strategic priorities About You Basic Qualifications: The ideal candidate brings a strong foundation in the biotech/pharmaceutical industry, combined with proven expertise in Project/Program Management. A scientific background and Medical Affairs experience are highly preferred. Education Bachelor of Science (BS) required Advanced degree in a scientific discipline strongly preferred Experience Minimum 5 years of project/program management experience within biotech/pharma, clinical, or scientific environments Demonstrated ability to translate strategic objectives into actionable tactical plans Proven track record of managing complex, cross-functional programs from initiation through completion with minimal supervision Medical Affairs experience preferred Core Competencies 🔹 Program Management Excellence Deep understanding of project/program management methodologies, frameworks, and best practices Skilled in end-to-end project ownership, including scope, timelines, risk management, and budget oversight Proficient in developing and maintaining reporting dashboards with key performance metrics using harmonized organizational tools 🔹 Leadership & Collaboration Demonstrated ability to lead and influence cross-functional teams within a matrix environment Strong management skills with the ability to engage effectively at all organizational levels Proven ability to foster a culture of teamwork, accountability, and collaboration 🔹 Communication & Organization Exceptional interpersonal and communication skills, both written and verbal Highly organized with the ability to manage competing priorities and tight deadlines with professionalism and composure Comfortable operating in a fast-paced, dynamic environment with shifting priorities Technical Skills Advanced proficiency in Microsoft Office Suite (Word, Excel, PowerPoint, Outlook) Working knowledge of project/program management software (e.g., SharePoint Apps, MS Project, or equivalent tools) Why Choose Us? • Bring the miracles of science to life alongside a supportive, future-focused team. • Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally. • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave. • Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs. • Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science. • Help improve the lives of millions of people globally by making drug development quicker and more effective. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse wor
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