Office Manager / Executive Assistant

Lycia Therapeutics (Nasdaq: LYCA) is a clinical-stage biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop therapeutics that degrade extracellular and membrane-bound proteins. These proteins drive a wide range of difficult-to-treat diseases, including autoimmune, inflammatory, and allergic conditions. Lycia was established in 2019 in collaboration with academic founder and Nobel Laureate Carolyn Bertozzi, Ph.D., professor of chemistry and HHMI investigator at Stanford University. In October 2026, Lycia completed an initial public offering, and its common stock now trades on the Nasdaq Global Select Market under the ticker symbol “LYCA.” Lycia is headquartered in South San Francisco. Visit https://lyciatx.com/ for more information. The Role: The Executive Assistant/Office Manager provides direct administrative support to Lycia’s Chief Business Officer, Chief Scientific Officer, and Chief Medical Officer, coordinates interviews for our hiring teams, and keeps our South San Francisco office running smoothly day to day. Working alongside Lycia’s other Executive Assistant, this role also serves on the company’s safety committee and leads the planning of our social and culture events. The ideal candidate is detail oriented, resourceful, and proactive, exercises sound judgment with confidential information, and is energized by a mix of executive support, recruiting coordination, and hands-on office work. This is an on-site position based in our South San Francisco office, with occasional travel to support advisory board meetings. Key Responsibilities: Office Management: Keep Lycia’s office space organized, presentable, and functional. Serve as a liaison with building management and office vendors on office-related requests. Maintain a well-stocked kitchen, track supply inventory, and order general office supplies; manage purchasing and vendor relationships for the office within budget. Set up conference rooms and audiovisual and IT equipment for meetings Manage incoming and outgoing mail and shipments. Executive Support: Manage complex calendars for the Chief Business Officer, Chief Scientific Officer, and Chief Medical Officer, proactively resolving conflicts and protecting time for top priorities. Coordinate domestic and international travel, including itineraries, bookings, and last-minute changes. Coordinate logistics for internal and external meetings, including scheduling, venues, catering, materials, and meeting setup, and travel to support these meetings on-site as needed. Handle confidential information with discretion, in accordance with Lycia’s confidentiality and insider trading policies. People & Culture: Schedule and coordinate interviews across the R&D organization, including multi-interviewer and on-site interview days. Support onboarding of new hires, partnering with hiring managers and HR on workspace, equipment, and company swag. Serve as a member of Lycia’s safety committee, and coordinate and schedule safety trainings for employees. Coordinate team events, such as offsites, happy hours, and company celebrations, that strengthen Lycia’s culture and sense of community. Qualifications: Bachelor’s degree or equivalent experience. 5+ years of experience as an executive assistant and/or office manager, including direct support of C-level executives. Experience coordinating advisory board or scientific meetings and interview scheduling preferred. Biotech or life sciences company experience preferred. Advanced proficiency with Microsoft 365 (Outlook, Word, Excel, PowerPoint). Excellent organizational and time management skills, with the ability to prioritize competing demands across multiple executives. Exceptional written and verbal communication and interpersonal skills. A high level of discretion and professionalism in handling confidential information. Ability to multitask and to work both independently and collaboratively in a fast-paced environment. A track record of anticipating needs, solving problems, and following through. Flexibility and adaptability to changing priorities. Ability to work on-site in South San Francisco and to travel occasionally to support external meetings. Ability to lift and carry office supplies and packages of up to 25 pounds.