Synthetic Chemist

Let’s build the future of medicine - together. Join Enveda as a Synthetic Chemist in Boulder, CO and help us transform natural compounds into life-changing medicines. We’re a team driven by curiosity and innovation - are you ready to make a difference? Boulder, CO | Full-Time | $125,000 – $135,000 | What Makes Us Enveda Life is smart, and we can learn from it. We’re reinventing drug discovery by harnessing nature’s intelligence. Our platform identifies new medicines four times faster than the industry standard because patients can’t wait. What sets Enveda apart isn’t just what we do - it’s how we do it. Our culture is built on creativity, collaboration, and deep respect for each other. We believe “People Create All Value”, and our success is driven by the extraordinary team turning our mission into reality every day. Our Momentum Unicorn status: Achieved following a $150 million Series D funding round in 2025 Discovery and innovation: Advanced our first drug candidate to Phase 1 trials in 2024 Award-winning culture: Newsweek: Top 100 Global #MostLovedWorkplaces (2025) Forbes: America’s Best Startup Employers (2024 & 2025) Newsweek: America’s Greatest Startup Workplaces (2025) Fast Company: Most Innovative Companies in 2026 These milestones reflect the impact of our team and we’re just getting started, but they’re only possible because of the diverse talent, perspectives, and relentless drive of our team, and people like you. Your Role in Our Mission At Enveda, every role drives impact. As a Synthetic Chemist on our Differential Platform Team, you’ll be at the forefront of discovery in metabolomics. Your expertise in small molecule synthesis, particularly within human-relevant chemical space, will be critical in accelerating our mission to identify unknown metabolites at scale. WHAT YOU'LL DO Own and design syntheses for our authentic standard library, from target list to confirmed compound, including efficient routes to structurally diverse natural metabolites and underexplored compound classes, designed so each compound can be confidently confirmed by LC-MS Develop and scale parallel or mixture synthesis workflows that enable rapid production of metabolite authentic standards for analytical validation Build the infrastructure and processes to maximize compound production, partnering with our Sample Management and Lab Automation teams on high-throughput experimentation and automation Translate computationally predicted molecular structures into confirmed, fully characterized compounds, closing the loop between data science and wet-lab chemistry, fast enough that synthesis is never the bottleneck Establish best practices for synthesis prioritization, route scouting, and library design so the team can move quickly through large numbers of targets Work in tight feedback loops with analytical chemists and data scientists who are predicting novel metabolite structures from mass spectrometry data at scale Support the metabolomics teams who rely on synthetic standards to validate discoveries, and the drug discovery teams who build on the metabolites your standards help confirm Help shape Enveda's compound collection strategy, deciding which regions of chemical space to explore next and how to build a library with lasting scientific value WHAT WE'RE LOOKING FOR A PhD in synthetic organic chemistry with 2+ years of hands-on experience in small molecule synthesis design, execution, and analysis Someone energized by variety: comfortable pivoting between compound classes, adapting routes on the fly, and working across dozens of distinct scaffolds rather than a single total synthesis campaign A chemist who genuinely enjoys working at the boundary of computation and synthesis, and who sees data-driven target selection as an opportunity rather than a constraint Hands-on experience running library, parallel, or high-throughput synthesis at the bench (you ran the plates, not only designed them), with a track record of delivering compounds on a timeline Comfortable using LC-MS to interpret complex mixtures, not just to monitor reactions Out-of-the-box thinking, the ability to envision and build capabilities, and the ability to work effectively within a multi-disciplinary team Experience with high-throughput experimentation (HTE) and automation platforms is a plus Someone who enjoys challenging problems, thinking big, and stretching the bounds of what's possible