Director, Scientific Technology & Laboratory Systems

Sarepta Therapeutics Cambridge, MA Updated 27 September 2026
PharmaBiotechRegulatory AffairsQuality Assuranceemacroinform

Job description

Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne. We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas: Physical and Emotional Wellness ​Financial Wellness Support for Caregivers For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us The Importance of the Role The Director, Scientific Technology & Laboratory Systems is the people and process leader accountable for Sarepta's scientific technology platforms and laboratory technology operating model. This leader directs multiple teams through subordinate managers and senior technical leaders, with responsibility for laboratory applications, instrument and endpoint technology services, business analysis, software development, portfolio governance, service delivery, vendor management, technology lifecycle planning, and laboratory technology risk management. The Director partners with Research, Development, Quality, Manufacturing, Information Security, Validation, and other business and IT functions to translate scientific and operational needs into practical strategies, multi-year roadmaps, prioritized investments, and reliable solutions. The role is approximately 75% strategic and 25% operational and requires a leader who can build a high-performing organization, establish scalable processes, challenge architecture decisions, and selectively advance automation, AI, and digital laboratory capabilities based on validated business need. The Position Sarepta is seeking a strategic, business-oriented technology leader to direct the Scientific Technology and Laboratory Systems organization. This role is accountable for the performance and evolution of the processes, people, platforms, and services that enable laboratory operations across the company. The Director will lead managers and senior professionals spanning laboratory instrument and endpoint technology services, scientific applications, business analysis, and software development. The successful candidate will establish clear accountability, mature governance and service-management practices, and create integrated multi-year roadmaps covering business demand, platform capabilities, upgrades, obsolescence, technical debt, operational resilience, and emerging technology opportunities. This leader will maintain sufficient technical depth to evaluate options and challenge architecture decisions, while achieving results primarily through managers, process leadership, cross-functional influence, and strong business partnership. The Opportunity to Make a Difference Provide leadership and direction through subordinate managers and senior technical leaders for an organization of approximately 20 employees and contractors supporting scientific technology platforms and laboratory technology operations. Build a high-performing, accountable organization by setting clear goals, defining decision rights, developing leaders, planning succession, managing performance, and strengthening capabilities across laboratory infrastructure, instrumentation support, applications, business analysis, and software development. Own and continuously improve the Lab Systems operating model, including demand intake, triage, prioritization, governance, resource planning, delivery oversight, service ownership, escalation, metrics, and continuous improvement. Develop and maintain an integrated multi-year scientific technology roadmap aligned with Research, Development, Quality, Manufacturing, and broader company strategies, including platform maturity, required upgrades, lifecycle milestones, obsolescence, technical debt, and support-model evolution. Direct the strategy, lifecycle, and service delivery for scientific technology platforms and laboratory systems, including LIMS, ELN, instrument software and integrations, laboratory endpoints, and related applications and services. Mature the LabVantage platform and support model, establishing sustainable ownership, development, release, support, integration, and vendor-management practices that meet current and future business needs. Establish an effective instrument technology lifecycle and asset-management program for laboratory computers, connectivity, supporting software, service status, risk, and technology obsolescence. Partner with business functions that retain budget ownership for new and replacement laboratory equipment. Build a formal Lab Systems demand and portfolio governance process; translate business priorities into sequenced initiatives, capacity and resource plans, investment recommendations, release plans, and measurable outcomes. Own departmental financial planning and budget execution for Lab Systems technology, services, staffing, contractors, and vendors. Provide transparent forecasts, identify tradeoffs, and maintain accountability for approved investments. Business functions retain capital ownership for laboratory instruments and replacement equipment. Manage strategic vendors and service providers, including relationship governance, contractual performance, service levels, issue escalation, roadmap alignment, and value realization. Own laboratory technology risk management, including identification, assessment, treatment planning, escalation, continuity considerations, unsupported technology, and operational resilience. Partner with Information Security on cybersecurity matters and with the designated Valida

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