Vice President, Head of Search & Evaluation

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide. Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.The Opportunity: Reporting to the Head of Corporate Development, The VP, Head of Search & Evaluation is a senior leader within the Corporate Development organization responsible for setting the strategy for, building the organization around, and leading the identification, assessment, and advancement of external innovation opportunities that support Revolution Medicines' portfolio strategy and long-term growth objectives. Working in close partnership with leaders across Research, Development, Commercial, Corporate Strategy, Portfolio Management, and Executive Management, this individual will lead the company's search and evaluation activities across discovery- and clinical-stage opportunities. The role is accountable for developing and maintaining a robust pipeline of external opportunities, driving rigorous opportunity assessments, shaping strategic recommendations that inform portfolio and partnering decisions, and building a high-performing Search & Evaluation team with the capabilities and leadership depth to support the company's growth. The successful candidate will combine deep scientific and business acumen with exceptional organizational leadership, strategic judgment, and executive communication skills. This individual will serve as a key connector across the organization and a senior external-facing leader, ensuring that external innovation efforts are aligned with corporate strategy, therapeutic area priorities, and emerging opportunities in precision oncology and related fields. They will create an environment in which talented team members can exercise judgment, grow as leaders, and independently drive high-quality search and evaluation work at scale. Responsibilities External Innovation Strategy and Opportunity Identification Set the strategic direction for the company's search and evaluation of external innovation in partnership with senior cross-functional and executive stakeholders. Develop and execute search strategies that align with Revolution Medicines' research, development, and commercial priorities. Oversee the full portfolio of discovery- and clinical-stage search and evaluation activities, setting priorities and deploying team resources to maintain a robust pipeline of external opportunities aligned with portfolio priorities. Build an external sourcing engine and lead proactive opportunity identification through engagement with biotechnology companies, academic institutions, investors, entrepreneurs, and other innovation ecosystems, while enabling team members to develop and own high-value external relationships. Partner with Portfolio Management, Disease Strategy, Research, and Development leaders to identify areas where external innovation can create strategic value and enhance portfolio competitiveness. Maintain a comprehensive understanding of relevant scientific, clinical, and competitive landscapes to identify emerging opportunities and trends. Opportunity Assessment and Diligence Leadership Provide leadership and oversight for cross-functional diligence and opportunity assessments, ensuring teams integrate scientific, clinical, commercial, strategic, operational, and financial perspectives into clear executive recommendations. Establish and continuously raise the bar for evaluation frameworks, decision criteria, and diligence standards that enable the team to deliver consistent, rigorous, and efficient assessments. Mobilize and guide cross-functional diligence teams across Research, Clinical Development, Regulatory, Commercial, Finance, Intellectual Property, Legal, and other functions, while empowering Search & Evaluation leaders to independently drive individual opportunities. Ensure key risks, opportunities, and strategic considerations are thoroughly evaluated and clearly communicated to decision-makers. Develop balanced recommendations regarding prioritization, resource allocation, and partnership strategy. Portfolio and Governance Leadership Establish and maintain scalable frameworks, operating rhythms, and governance for opportunity evaluation, diligence, prioritization, resource allocation, and decision-making. Provide portfolio-level oversight of opportunities moving through evaluation and governance processes, ensuring efficient review, transparency, organizational alignment, and clear accountability across the team. Prepare and present, and coach the team to prepare and present, opportunity assessments, landscape analyses, strategic recommendations, and diligence findings to senior leadership, governance committees, and other executive audiences. Partner with Portfolio Management, Corporate Development leadership, and executive stakeholders to shape external innovation priorities as corporate strategy and portfolio needs evolve. Support portfolio planning efforts through identification and assessment of external opportunities that address strategic gaps or accelerate growth objectives. Partnership with Transactions & Partnering Partner closely with the Head of Transactions & Partnering and their organization to advance prioritized opportunities through transaction execution and negotiation. Ensure key diligence findings, strategic considerations, and identified risks are effectively incorporated into transaction strategy and deal structuring. Guide negotiation preparation and executive decision-making by ensuring that scientific, clinical, commercial, and strategic context from the Search & Evaluation team is translated into clear deal priorities and trade-offs. Facilitate seamless transition of opportunities from evaluation through transaction execution. Team and Organizational Leadership Build, lead, and scale a high-performing Search & Evaluation organization with the scientific breadth, business judgment, and leadership capability to support the company's evolving business development and portfolio objectives. Recruit, develop, coach, and retain exceptional talent; establish clear roles, expectations, and career paths; and create leadership depth within the function. Create a culture of scientific rigor, strategic thinking, ownership, collaboration, healthy debate, and accountability, with high standards for both individual performance and team outcomes. Develop and empower team members to independently lead search strategies, external relationships, opportunity assessments, cross-functional diligence, and executive recommendations, while providing appropriate coaching and escalation support. Allocate resources and priorities across the Search & Evaluation portfolio, balancing near-term transaction needs with proactive search, capability building, and longer-term strategic opportunities. Build scalable processes, tools, knowledge systems, and best practices that increase the team's effectiveness, consistency, speed, and organizational impact as the company grows. Partner with Corporate Development leadership to shape the broader organization, including talent strategy, ways of working, operating model, and cross-functional engagement. External Relationship Management Build and maintain senior-level relationships