Senior Program Manager

Career Category Project Management Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Program Manager What you will do Let’s do this. Let’s change the world. The Senior Program Manager partners closely with an R&D Quality Associate Vice President for Clinical & Research Quality and Senior Directors for R&D GxP Audit and Operational Excellence to drive execution of strategic priorities. This role integrates strategic planning, operational excellence, organizational effectiveness, communications, portfolio coordination and transformation to enable leadership focus on business priorities. In close partnership with the RDQ Strategy & Performance and Operations (SPO) Director, this role helps translate enterprise and RDQ strategic priorities into coordinated operational execution across supported capabilities while ensuring consistent approaches, templates, governance, and business processes across the organization. Key responsibilities include: Strategic Planning & Execution Partner with capability leaders in Clinical & Research Quality, R&D GxP Audit and Operational Excellence to develop and execute annual strategic priorities, operating plans and measurable deliverables Coordinate execution of RDQ priorities across supported capabilities through standardized templates, governance, and business processes to ensure consistent delivery Monitor organizational objectives, milestones and dependencies Identify operational risks and recommend mitigation strategies Support the Operational Excellence Senior Director in centrally coordinating and tracking emerging and ongoing business initiatives and due diligence/mergers & acquisitions to enhance RDQ visibility and inform functional resource planning across RDQ Business Operations Partner with capability leaders in Clinical & Research Quality, R&D GxP Audit and Operational Excellence to co-lead planning and execution of leadership team meetings and organizational forums (e.g. Therapeutic Area portfolio reviews, performance management reviews) Assist in development presentations for governance, dashboards, decision materials, and meeting content Drive follow-up of leadership decisions and action items Coordinate preparation of standardized business materials, executive updates, operating review content, and leadership communications using common RDQ templates and formats to promote consistency and efficiency Serve as the primary operational liaison between supported capability leadership and the Strategic Performance & Operations Director to coordinate information flow, deliverables, and business planning activities Functional Transformation and Program Management Coordinate key functional initiatives related to Clinical & Research Quality, R&D GxP Audit and Operational Excellence Partner with the Strategic Planning & Operations Director to operationalize enterprise initiatives within supported capabilities, ensuring strategic direction is translated into actionable implementation plans Monitor timelines, deliverables, and interdependencies Facilitate strategic workshops and planning sessions for key functional initiatives Support implementation of transformation (e.g. new operating models, organizational changes) Engage with Continuous Improvement for Organizational Change Management strategies and best practices May support special projects, as assigned by manager Operational Excellence Improve organizational effectiveness for Clinical & Research Quality, R&D GxP Audit and Operational Excellence through standardized processes by implementing standardized business processes, governance practices, templates, and tools that enable consistent execution across RDQ Build and/or manage organizational knowledge repositories (e.g. SharePoint, MS Teams) Support workforce planning and organizational capacity planning Monitor organizational health metrics and recommend improvement actions Leadership Support Serves as a trusted partner to capability leadership by translating strategic direction into coordinated execution plans, tracking progress, and facilitating alignment across functions Collaborates closely with the Strategic Performance & Operations director and peer Program Managers to ensure enterprise priorities, governance activities, and leadership requests are executed consistently across RDQ Thinks strategically while executing operationally Applies continuous improvement mindset and problem-solving skills in proactively identifying opportunities to improve operational excellence Ability to navigate ambiguity and changing priorities with agility in a fast-based, dynamic environment Influences without authority What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications Basic Qualifications: Doctorate degree and 2 years of relevant experience (program management, business operations, quality assurance, R&D) OR Master's degree and 4 years of relevant experience (program management, business operations, quality assurance) OR Bachelor's degree and 6 years of relevant experience (program management, business operations, quality assurance, R&D) OR Associate's degree and 10 years of relevant experience (program management, business operations, quality assurance, R&D) OR High school diploma/GED and 12 years relevant experience (program management, business operations, quality assurance, R&D) Preferred Qualifications: Experience supporting leadership teams Advanced skills in program or portfolio management in a matrixed organization Demonstrated ability to manage multiple priorities while maintaining attention to detail Experience developing strategic roadmaps and operating plans Proven track record with successfully integrating global teams with effective collaboration and high emotional intelligence Proficiency with collaboration and AI tools (e.g. Microsoft PowerPoint, Excel, Teams, S