Senior Tax Manager, Japan & APAC (JAPAC), ex China

About us BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 10,000 colleagues spans five continents, with administrative offices in Basel, Beijing, and Cambridge, U.S. To learn more about BeOne , please visit www.beonemedicines.com and follow us on LinkedIn and X (formerly known as Twitter). BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. Job Description: As BeOne Medicines continues to grow its business in Japan and across the Asia Pacific region, we are seeking a Senior Tax Manager, Japan to provide strong local and regional tax leadership and operational support. The Senior Tax Manager, Japan & APAC will be the regional tax team's senior, hands-on lead for Japan. The role will take primary responsibility for the quality and timely delivery of Japan tax compliance, tax accounting, tax authority matters, transfer pricing execution, and day-to-day tax advice. The role will also support selected APAC markets and regional projects. Working closely with the Associate Tax Director, global tax teams, Finance, Legal, Treasury, HR, Medical, Commercial, Clinical Operations, and external advisers, the role will translate technical requirements into practical controls, clear decisions, and sustainable processes. The successful candidate should be technically strong, practical, detail-oriented and digitally capable, with the ability to work fluently in both Japanese and English. This role requires someone who can bridge Japanese local requirements with global tax expectations and help strengthen tax controls, documentation and process discipline. Essential Functions of the job: Japan tax leadership and compliance Own and manage the Japan tax compliance calendar, tax risk register, key controls, and internal review process Lead the preparation, coordination with external tax advisors, and review of Japanese corporate income tax, consumption tax, withholding tax, local tax, and other recurring filings, payments, registrations, and notifications Critically review tax returns, calculations, workpapers, and advice prepared by external consultants; challenge assumptions and ensure accuracy, completeness, and consistency before internal approval or filing Ensure tax filings and positions are supported by reliable source data, reconciled to SAP and the general ledger, and evidenced through clear, audit-ready documentation Provide practical guidance on vendor, healthcare professional, employee, and cross-border withholding tax matters, working with the relevant process owners to establish clear responsibilities and controls Tax accounting and reporting Manage Japan quarterly and annual tax accounting, including current and deferred tax, tax provisions, effective tax rate analysis, return-to-provision, and uncertain tax positions, as applicable Review tax accounts, balance sheet reconciliations, tax payments, forecasts, and cash tax requirements, and drive timely resolution of reconciling items Support statutory financial statements, group reporting, audit requests, and tax disclosures under local requirements and US GAAP, including ASC 740 concepts Tax audits and controversy Act as the primary tax contact for Japan tax authority enquiries, reviews, and audits, including development of response strategies and management of information requests and deadlines Coordinate internal stakeholders and external advisers, maintain clear records of submissions and decisions, and ensure agreed remediation actions are implemented Transfer pricing and international tax Manage Japan transfer pricing execution for distribution, R&D service, funding, and other related-party arrangements, including target setting, operational calculations, true-ups, and financial statement alignment Coordinate and review benchmarking studies, local files, related-party disclosures, CbCR-related requirements, intercompany agreements, and supporting documentation Advise on cross-border payments and transactions, including treaty access, withholding tax, permanent establishment, indirect tax, and other international tax considerations Support Pillar Two, supply chain, customs, financing, restructuring, and other global or regional tax initiatives affecting Japan Business partnering and transaction support Provide timely, commercially practical tax advice on contracts, product launches, pricing, importation and distribution models, clinical trial and healthcare professional arrangements, employment matters, and business change Partner proactively with Accounting, Accounts Payable, Treasury, Legal, HR, Payroll, Medical, Commercial, Supply Chain, and Clinical Operations to identify risks early and implement workable solutions Clearly communicate tax positions, options, risks, and recommended actions in Japanese and English to both technical and non-technical stakeholders APAC regional support Support selected APAC markets on direct and indirect tax, withholding tax, tax accounting, transfer pricing, R&D incentives, tax audits, entity establishment, and other priority matters Contribute to regional tax governance, control improvement, process standardisation, documentation, digitalisation, and tax technology initiatives Provide cover and surge support for regional compliance cycles and projects, while maintaining Japan as the role's primary responsibility External adviser and stakeholder management Manage relationships with external tax advisers, including scopes of work, fee proposals, budgets, timelines, deliverable quality, and performance Maintain internal ownership of tax positions and deliverables rather than relying solely on advisers, escalating material issues with a clear recommendation Build trusted, constructive relationships with local management and regional and global tax stakeholders Team support and capability development Provide day-to-day technical guidance, review, and mentoring to the Tax Specialist and other team member(s) Develop practical procedures, review checklists, templates, and knowl