Senior Director, Brand Experience & Engagement

Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases. Our core business strategy combines our experienced leadership team with a disciplined product candidate acquisition approach to identify, acquire and develop product candidates globally that we believe can provide superior clinical benefits to patients living with autoimmune diseases. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. We believe that obexelimab’s unique mechanism of action and self-administered, subcutaneous injection regimen may broadly and effectively address the pathogenic role of B cell lineage in chronic autoimmune disease. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Zenas’ earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcγRIIb monoclonal antibody. We are seeking top talent who share our commitment to patients and have a track record of success in acquiring, developing and commercializing products across the globe. Our colleagues have an opportunity to engage in a fast-paced learning environment and experience individual and organizational success as we work towards becoming a global immunology and autoimmune disease leader, while living our values of Transparency, Relationships, Urgency, Excellence and Innovation – TRUE Innovation!Position Summary: Zenas is seeking a strategic, digitally fluent marketer and commercial leader to help shape the obexelimab brand strategy and how it comes to life in market — leading the brand and go-to-market experience for the asset's first anticipated launch in IgG4-Related Disease and building scalable solutions for future launches. Reporting to the SVP, Commercial Strategy & Corporate Affairs, this leader will partner closely with the Brand Director to translate obexelimab’s brand strategy into a connected brand experience across digital, content, CRM, disease awareness, patient/caregiver education, congress extensions, and other customer engagement channels. Partnering closely with the Senior Brand Director, they contribute to brand positioning and own its expression as a consistent, compelling experience across every audience segment, channel, and touchpoint. This leader brings a modern approach to commercialization — connecting marketing, field, digital, and patient services into one commercial engine. The payoff: a scalable, externally visible brand presence that lets lean teams launch with the impact of a far larger organization. Key Responsibilities: Brand & Go-to-Market Strategy Leads the go-to-market engagement strategy and brand experience activation for obexelimab in partnership with the Brand Director, defining how the brand reaches and engages each audience across marketing, field, digital, and patient services as one connected commercial system. Designs the customer engagement model and journey architecture, sequencing how and when the brand shows up from pre-launch market development through commercialization. Co-develops brand positioning with the Senior Brand Director, and owns its expression as a consistent, compelling experience across every channel and touchpoint. Aligns field, marketing, and patient-services engagement into a single orchestrated plan, eliminating the disconnects that fragment the customer experience. Commercial Strategy Contributes to the obexelimab commercial strategy as a member of the launch leadership team, bringing the brand-experience and customer-engagement perspective into strategic decisions. Informs forecasting and commercial-planning assumptions with engagement insight, channel performance, and customer-journey data. Partners across brand, market access, and field leadership to ensure brand, access, and engagement strategies reinforce one another. Turns commercial strategy into brand-experience and GTM plans — and feeds engagement and market signal back to sharpen it. Translates brand and commercial strategy into integrated brand experience, digital engagement, and content activation plans. Digital Engagement & Connected Customer Experience Leads digital and content execution across brand-facing initiatives, including website experiences, CRM journeys, modular content, congress digital extensions, social amplification, and disease education campaigns. Builds and maintains performance measurement frameworks for digital campaigns, content engagement, and channel effectiveness, using data to continuously sharpen strategy and investment. Ensures brand communications across all digital and external channels are consistent, compliant, and reinforce a single, compelling brand story throughout the launch lifecycle. Partners with the SVP, Commercial Strategy & Corporate Affairs, to align disease awareness, brand storytelling, media/social opportunities, and external visibility initiatives with commercial strategy. Disease Awareness & Community Communications Leads disease awareness communications strategy, including unbranded digital content, patient-facing web properties, disease education, and community-oriented brand presence in the IgG4-RD space. Partners with Patient Advocacy, HUB Patient Services, and Corporate Affairs to align external visibility, community engagement, and disease awareness with commercial brand strategy. Develops and delivers compliant patient- and caregiver-facing communications assets, including disease awareness content, digital education, and CRM journeys, in close partnership with Medical Affairs and Legal/Regulatory. Develops plain-language, human-centered content that makes complex science and disease education understandable, credible, and engaging. Ensures disease awareness and patient communications are fully integrated with the broader brand narrative and launch communications calendar, not treated as a separate workstream. Commercial Modernization & Innovation Uses analytics to optimize channel mix, message performance, audience activation, and investment decisions across the integrated channel ecosystem. Identifies and operationalizes responsible use of AI, automation, and modular-content approaches that accelerate execution and personalization at scale. Establishes the operating model, workflows, and capabilities that make modern, data-driven engagement a repeatable strength rather than a one-time launch effort. Cross-Functional Launch Leadership, Agency & Budget Management Serves as a connector across Marketing, Corporate Affairs, Advocacy, Patient Services, Medical Affairs, Analytics, Legal, Regulatory, Compliance, IT, and agency partners. Leads agency partners and external vendors, setting the brief, guarding the brand experience, and holding partners accountable to quality and speed within budget. Owns the marketing budget for the brand experience and engagement portfolio, allocating investment against the highest-impact opportunities and reporting on return. Establishes KPIs, dashboards, and measurement frameworks for cross-channel engagement, content performance, and customer activation. Develops business cases and gains senior-leadership ali