Lead, US Hematology Pipeline Commercialization

Job Title: Lead, US Hematology Pipeline Commercialization Location: Cambridge, MA About the Job Sanofi Specialty Care has pioneered the development and delivery of transformative therapies for patients affected by debilitating diseases for more than 30 years. We achieve this through world-class science, close collaboration with the global patient community, and the compassion and commitment of our employees. Within Sanofi Specialty Care, the US Rare Blood Disorders franchise is committed to advancing care for patients with complex hematologic and immunologic conditions. The franchise has a diverse and rapidly growing portfolio, including industry-leading products in hemophilia; the first and only approved medicines in acquired thrombotic thrombocytopenic purpura and indolent and advanced systemic mastocytosis, Cablivi and Ayvakit, respectively; and now expanding rapidly to other under-served hematologic disorders with the launch of Wayrilz in Immune Thrombocytopenia (ITP). The Lead, US Hematology Pipeline Commercialization will serve as the US commercial architect for future Wayrilz indications. This role will have primary responsibility for shaping the US commercial strategy, market development approach, investment plan, and launch readiness for Wayrilz in warm Autoimmune Hemolytic Anemia (wAIHA) and sickle cell disease. This role will also contribute to the US commercialization strategy for Wayrilz in IgG4-related disease and help evaluate additional future indications and opportunities. The successful candidate will rapidly build a deep understanding of patients, providers, treatment pathways, market dynamics, and emerging competition. They will translate incomplete and evolving information into clear strategic choices and help define what must be true for future indications to succeed in the US market. This role requires strong strategic judgment, executive presence, commercial acumen, and the ability to lead through influence in a highly matrixed environment. The role reports to the Head of Rare Hematology Marketing and will work closely with the US ITP Marketing Lead, the Global Wayrilz team, and other cross-functional leaders. What Success in Role Looks Like The successful candidate will ensure that future hematology indications are shaped with the US market in mind from the earliest stages of development. They will create clear and differentiated commercial strategies, influence evidence and investment decisions, build organizational alignment, and establish strong launch foundations well before approval. They will be recognized as a trusted partner across US, Global, Medical, R&D, Market Access, and the broader Rare Blood Disorders organization—and as a leader who can turn ambiguity into strategy, strategy into action, and pipeline potential into meaningful impact for patients. Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. About Sanofi: We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives Main Responsibilities Culture and Leadership Embody Sanofi’s Take the Lead values: Aim Higher, Act for Patients, Be Bold, and Lead Together. Bring an enterprise mindset and actively apply lessons, capabilities, and best practices from across Sanofi. Create clarity, alignment, and momentum across complex cross-functional teams. Demonstrate sound judgment, personal accountability, integrity, and a strong commitment to patients. US Commercial Strategy, Launch and Market Development Lead development of the US commercial strategy for Wayrilz in wAIHA and sickle cell disease. Contribute to the US commercialization strategy for Wayrilz in IgG4-related disease. Translate patient, provider, access, competitive, and market insights into clear strategic choices and commercial priorities. Define the critical success factors for each indication, including target patient populations, treatment positioning, customer segments, evidence needs, access considerations, and market development requirements. Evaluate competitive scenarios, market evolution, treatment pathways, and potential barriers to adoption. Establish launch readiness plans, key milestones, decision points, organizational requirements, and cross-functional accountabilities. Advocate for appropriate pre-launch investments, including competitive intelligence, primary and secondary market research, disease education, patient insight generation, advocacy engagement, and customer development. Build effective relationships with external experts, thought leaders, patient advocacy organizations, and other stakeholders. Select and lead agency partners in support of strategy development, market preparation, and launch planning. AI and the Marketer of the Future Build and apply strong AI and large-language-model fluency across commercialization planning. Explore new approaches to insight generation, competitive intelligence, forecasting, content development, market research, and customer engagement. Partner across functions to identify opportunities to increase the speed, quality, and personalization of disease-state experiences for healthcare professionals and patients. Encourage responsible experimentation while ensuring appropriate governance, compliance, and human oversight. Development and Evidence Strategy Represent the US commercial perspective within Global development and commercialization discussions. Provide commercial input into target product profiles, clinical development assumptions, evidence-generation priorities, endpoints, patient populations, and differentiation strategies. Identify evidence gaps that may affect future adoption, access, treatment choice, or long-term commercial potential. Ensure that development and evidence plans reflect the realities of US clinical practice and customer decision-making. Forecasting, Investment, and Business Planning Inform long-term revenue forecasts, patient-based forecasts, scenario planning, and commercial assumptions for future indications. Develop clear investment cases and recommendations for OpEx, market development, evidence generation, and launch preparation. Partner with Finance, Business Operations, Market Access, Global, and other functions to evaluate commercial potential and resource requirements. Establish measurable success indicators and proactively identify risks, dependencies, and mitigation plans. Access and Patient Experience Partner closely with Market Access to inform pricing, contracting, reimbursement, and access strategies for indications in development. Anticipate payer evidence requirements and potential barriers to coverage. Wor