East Coast Hub & Commercialization Executive Operations Manager

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.The Opportunity: The East Coast Hub & Commercialization Executive Operations Manager serves as a trusted operational and administrative partner to the Chief Global Commercialization Officer (CGCO) and the eCLT while leading day-to-day operation of Revolution Medicines' East Coast office in Plainsboro, NJ. This role provides executive support, oversees site operations, and coordinates cross-functional initiatives to enhance team effectiveness, foster site-wide alignment and co-create an exceptional employee experience with senior leaders. The role also serves as the coordinating lead for the Commercialization administrative community, driving best practices, consistent ways of working and strong collaboration among administrative team members supporting leaders across the global Commercialization organization. The successful candidate will thrive in a fast-paced environment, exercises independent and sound judgment, builds strong partnerships across the organization, and help establish scalable office operations that support continued growth. Key responsibilities include: As the operations partner/ lead administrative support to the CGCO, this role enables leadership effectiveness through proactive coordination, executive support, and cross-functional collaboration. Manage the CGCO's complex global calendar, strategically balancing competing priorities, proactively resolving scheduling conflicts, and ensuring executive readiness across global time zones. Coordinate leadership engagement across CLT and the Commercialization organization by partnering with administrative team members and cross-funtional stakeholders to optimize scheduling, meeting effectiveness, and organizational alignment. Lead the planning and execution of executive travel, leadership meetings, off-sites, town halls, and business reviews, including logistics, follow-up, and action item tracking. Coordinate special projects and strategic initiatives on behalf of the CGCO and Commercialization Leadership Team (CLT). Manage consulting agreements, statements of work, purchase requests, and vendor engagements in partnership with Legal, Procurement, and Finance. Build trusted partnerships across the organization while handling sensitive information with the highest level of confidentiality and discretion. Lead coordination of the Commercialization administrative community, establishing best practices, consistent ways of working, and shared support standards to drive operational effectiveness and collaboration. Partner with functional administrative team members and business leaders to develop, implememt, and continuously improve administrative support models, workflows, and cross-functional operating practices. Support onboarding, integration, and capability development of functional administrative team members by providing guidance, tools, resources, and best practices. Serve as a resource to the Commercialization administrative community, fostering knowledge sharing, operational excellence, and continuous improvement. Participate in the corporate administrative community, build strong partnerships and advance collaboration across administrative teams. May serve as the commercialization admin representative when needed. As the Operational Lead for the East Coast office, this role ensures a productive, well-functioning workplace and supports the site’s continued growth and scalability . Lead operational readiness of the East Coast office, serving as the primary contact for building management, workplace service providers, and facilities vendors. Oversee day-to-day office operations, including workplace services, access management, conference room technology, mail services, office supplies, food and beverage programs, and other workplace resources. Manage vendor relationships and service delivery to ensure seamless workplace experience. Identify and implement improvements to workplace experience, operational efficiency, and office scalability. Partner with HR, Facilities, EHS, Corporate Communications, and the broader administrative community to support office space planning, employee onboarding, workplace communications, and employee engagement initiatives. Manage office operating budgets, maintain operational records, and documentation, and monitor workplace-related expenditures as appropriate. Required Skills, Experience and Education: Bachelor's degree or equivalent combination of education and experience. 10+ years of progressively responsible experience providing executive support to senior leaders and/or leading workplace operations within a fast-paced environment. Experience supporting C-suite executives and leadership teams within a matrixed global organization, including complex global calendar management, travel planning, and meeting coordination. Experience with setting up and managing brand new office operations, workplace services, facilities vendors, or corporate office environments. Demonstrated ability to independently manage multiple competing priorities, exercise sound judgment and discretion, anticipate needs, identify risks, and proactively implement solutions. Exceptional organizational, project management, and time management skills, with strong attention to detail and the ability to drive execution of cross-functional initiatives. Strong business acumen, communication, and interpersonal skills, with the ability to build productive relationships across functions, levels, and external partners. Able to handle highly confidential information with professionalism, integrity, and discretion. Proactive, solution-oriented mindset with the flexibility to thrive in a dynamic, high-growth environment. Proficiency in Microsoft Office Suite, including Outlook, PowerPoint, Word, Teams, and Excel. Preferred Skills: Biotechnology, pharmaceutical, or life sciences industry experience. Experience establishing or supporting operations for a growing office location or regional hub. Experience with contract management, procurement processes, budget tracking, and vendor administration. Familiarity with project management tools such as Smartsheet, Asana, or similar platforms. #LI-TS1 #LI-HybridThe base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religio