Research Scientist I - Formulation/Raziskovalec I

Salary Range: €20,300.00 - €37,700.00 Job Description Summary #LI-Hybrid Location: Mengeš, Slovenia Role Purpose: Our R&D unit in Mengeš is looking for a motivated scientist in field of Formulation development to join our unit and help us develop a diverse portfolio of biotherapeutic modalities. As a Research Scientist you must demonstrate knowledge of pre-formulation/formulation and characterization to evaluate the developability of various biologics modalities covered by Novartis Biomedical Research and Development units, ranging from traditional antibodies to advanced biologics formats and mixed modalities. You will help shape the overall formulation strategy for large biomolecules before the project transition from research into early phase development and help funnel out unfavorable candidates with respect to formulation assessment. We offer a stimulating work environment, ample opportunities for growth and development, and the chance to make a significant impact on the future of medicine. If you are a motivated and talented scientist with a passion for biomedical research, we invite you to apply and become a part of our dynamic team at Novartis. Naša R&D enota v Mengšu išče motiviranega raziskovalca na področju razvoja formulacij, ki se bo pridružil naši enoti in nam pomagal razvijati raznolik portfelj bioterapevtikov. Kot raziskovalec morate izkazovati znanje s področja predformulacijskih in formulacijskih študij ter karakterizacije za oceno razvojne primernosti različnih bioterapevtikov, ki jih obravnavajo enote Novartis Biomedical Research and Development, od tradicionalnih protiteles do naprednih bioloških formatov in kombiniranih modalitet. Pomagali boste oblikovati celovito strategijo formulacij za biološke kandidate pred prehodom projekta iz raziskovalne faze v zgodnji razvoj ter pomagali izločiti neustrezne kandidate z vidika formulacijske ocene. Nudimo spodbudno delovno okolje, številne priložnosti za rast in razvoj ter možnost pomembnega vpliva na prihodnost medicine. Če ste motiviran in nadarjen raziskovalec s strastjo do biomedicinskih raziskav, vas vabimo, da se prijavite in postanete del naše dinamične ekipe v Novartisu. Job Description Key Responsibilities : Perform pre formulation assessment for monoconal antibodies , multispecific antibodies and other therapeutic proteins , including but not limited to solubility assessment and setup of formulation screening studies . P erform biophysical characterization methods such as DSC/DSF, dynamic light scattering (DLS), UV-Vis, turbidity , sub visible particle assessment , viscosity and other techniques that are LC based method (SEC,HIC) for characterizing therapeutic proteins . Utilize state-of-the art liquid handlers for compounding of formulations for large biotherapeutics to conduct stability studies on them Conduct physicochemical analytics methods for characterization of various formats of biotherapeutics in screening , formulation andlead optimization stages Operate and maintain instrumentations , perform data analysis and ELN documentation , and author method development and technical reports . Work in a highly interdisciplinary and collaborative environment as part of global project t eam s and contribute to data analysis and interpretation , making technical presentations