Director Global Trade Compliance

Job Description General/Position Summary The Director, Global Trade Compliance is responsible for developing, owning, maintaining, and executing global trade compliance business processes, global trade management systems, and associated regulatory compliance activities. This role supports all Vertex supply chain models—including finished goods distribution, commercial manufacturing, clinical materials, development, research shipments, and other cross-border movements—across all geographies in which Vertex operates. The Director leads the Global Trade Compliance (GTC) business process and regulatory compliance team, resolving operational challenges, advancing strategic solutions, and ensuring consistent, accurate, efficient, and compliant customs declarations and related activities that support Vertex and the patients we serve. Key Duties & Responsibilities Develop a deep understanding of Vertex’s supply chain operating models, including finished goods distribution, commercial manufacturing, clinical, development, and research materials. Lead the GTC team responsible for designing, implementing, and maintaining scalable trade compliance processes and systems aligned to these models. Lead the GTC team responsible for interpreting and operationalizing global trade compliance requirements, with particular focus on the United States, European Union, and United Kingdom. Identify and implement strategic, best-practice solutions that meet applicable requirements. Oversee trade compliance activities across import and export customs declarations, including customs valuation, tariff classification, country of origin, partner government agency requirements, duty-mitigation programs, export controls, and licensing. Drive the global strategy for GTC processes and systems in partnership with Supply Chain, Operations, Legal, Tax, Finance, Accounting, Regulatory, Data Technology and Engineering (DTE), Office of Business Ethics and Integrity (OBIE), and other relevant stakeholders. Monitor trade actions, legislation, and regulatory and administrative developments to identify changes that may affect Vertex. Partner with Government Affairs and other stakeholders to assess impacts and support advocacy activities, as appropriate. Develop and deploy processes and systems to monitor global tariffs and optimize duty costs across Vertex’s end-to-end supply chains. This includes inventory-management programs such as duty drawback, inward processing, and foreign-trade zones; end-use and availability programs, including U.S. prototype and tariff-suspension programs; and bilateral or multilateral free-trade agreements. Establish priorities based on business requirements and resource availability, enabling the GTC team to adapt effectively to evolving business and patient needs. Support governance and performance management of managed service providers, customs brokers, and other subject-matter experts performing critical trade compliance activities. Develop and implement operational and compliance metrics to support timely export, customs release, and delivery of shipments. Lead corrective and preventive action (CAPA) processes to address performance issues and drive continuous improvement. Serve as a key strategic partner to the Senior Director, Global Trade Strategy & Compliance in developing and executing a global trade compliance strategy and governance model that enables Vertex’s growth across markets, medicines, and modalities. Required Education Bachelor’s degree in International Trade, Business, Supply Chain, or a related field, or equivalent combination of education and experience. Advanced degree preferred. Required Experience 15&#43; years of progressive experience across global trade compliance activities within a pharmaceutical, biotechnology, life sciences, or similarly regulated global manufacturing organization. Experience gained through a trade compliance consulting firm or strategic service provider may offset a portion of direct industry experience. Demonstrated experience leading and developing high-performing teams in a global, complex operating environment. Required Knowledge, Skills & Abilities Proven track record of successfully leading, developing, and retaining high-performing teams. Deep understanding of pharmaceutical or life sciences supply chains and operations, including finished goods distribution, manufacturing, clinical, development, and research materials. Advanced knowledge of global trade compliance and export control regulations, with direct experience in the United States, European Union, and United Kingdom, as well as familiarity with requirements in other key countries and regions. Demonstrated ability to translate complex trade compliance and export-control requirements into practical, scalable solutions for pharmaceutical or life sciences operations. Strong strategic, analytical, and problem-solving skills, with the ability to identify risks, evaluate options, and drive sustainable solutions. Excellent communication and executive presence, including the ability to explain complex trade and regulatory topics clearly, concisely, and in a manner relevant to Vertex’s business, products, and stakeholders. Demonstrated ability to lead change and influence cross-functional stakeholders in a fast-paced, evolving organization. Experience with global trade management systems, other digital platforms, and the practical application of automation and artificial intelligence to improve trade compliance processes. Experience addressing European Union trade, customs, and VAT requirements, including the regulatory complexities associated with operating in the EU market. Experience developing and deploying effective trade compliance training programs in a manufacturing or similarly regulated environment. Familiarity with tax and accounting concepts, including transfer pricing, intellectual property, and standard costs, as well as experience developing compliant customs valuation programs that align with these concepts. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $178,200 - $267,200 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. </di