Sr Manager, Data/AI Solution Architect

Gilead Sciences 2 Locations Updated 22 September 2026
PharmaBiotechRegulatory AffairsQuality Assurancepythoncroinformaws

Job description

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description As part of Gilead’s enterprise AI strategy to accelerate insights and decision‑making, we are seeking an Sr Manager, Data/AI Solution Architect to lead the design of Data and AI solutions across the HR & LCCR Functions. In this role, you will partner closely with business stakeholders, and Data/AI Product Owners, Technical Delivery Leads and Platform Leads to determine the right solution architecture for predictive analytics and AI‑driven insights. You will drive technical excellence through architectural design, modeling approach, and platform selection—ensuring scalable solutions, aligned to Gilead standards, that translate complex digital needs into actionable insights. This position will report to the Director, Data/AI and is based in Foster City, CA (hybrid‑eligible). Key Responsibilities: Solution design & delivery: Partner with function business process leads across HR, Compliance, and Legal to assess needs and translate them into practical AI solution designs and serve as the technical lead across solutions. Model development & tuning: Build, fine-tune, and evaluate AI/LLM models grounded in policy, procedural, and regulatory requirements, and adaptable to Gilead-specific content, internal materials, and approved templates. Knowledge base engineering: Design and maintain retrieval-augmented (RAG) knowledge bases incorporating authoritative external guidance, corporate policy libraries, compliance frameworks and codes of conduct, and Gilead-specific documentation. Review & workflow automation: Develop reusable capabilities for document review, summarization, consistency and policy-alignment checking, citation accuracy, and risk flagging — with traceable citations back to source content. Data pipelines: Engineer secure, scalable ingestion and processing pipelines for diverse content types across enterprise support functions, including policy and procedure documents, employee-facing communications, training and enablement materials, internal narratives, external publications, and structured business records. Delivery through extended teams: Direct execution through engineers, vendor partners, and shared platform resources — setting technical direction, reviewing designs, ensuring quality, and driving solutions to production at a scale beyond individual delivery. Evaluation & quality: Establish evaluation frameworks, accuracy benchmarks, guardrails, and human-in-the-loop validation to ensure trustworthy, defensible, and auditable outputs. Stakeholder collaboration: Act as the bridge between business stakeholders and AI delivery — converting functional review and knowledge-work needs into trusted, auditable solutions that reduce cycle time and organizational risk. Drive adoption, enablement, and change management. Governance: Ensure solutions meet data privacy, confidentiality, security, and responsible-AI standards, with role-based access appropriate to sensitive enterprise content. MLOps: Implement model deployment, monitoring, versioning, and continuous improvement practices, and establish reusable architecture standards and delivery patterns across the portfolio. Basic Qualifications: Bachelor's Degree and Eight Years’ Experience OR Master's Degree and Six Years’ Experience Preferred Qualifications: 5&#43; years of experience in AI/ML engineering, with hands-on work building LLM/generative-AI applications (fine-tuning, RAG, prompt engineering). Strong programming skills in Python and modern ML frameworks. Experience designing knowledge bases and retrieval systems over large structured and unstructured sources. Experience with AWS cloud AI platforms and MLOps tooling. Solid data engineering fundamentals: pipelines, data modeling, and large-scale processing. Experience delivering a portfolio of solutions across multiple business functions, including leading delivery through engineering teams and external partners. Experience in pharmaceutical, biotech, life sciences, or other highly regulated industries. Familiarity with Tech policies, compliance, and governance workflows in a regulated enterprise environment. Experience with enterprise context build and automation Experience handling confidential and sensitive enterprise data, including HR and Legal with appropriate privacy controls. Experience with responsible AI, model governance, and validation in regulated environments. The salary range for this position is: Bay Area: $169,320.00 - $219,120.00. Raleigh: $146,200.00 - $189,200.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. <spa

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