Exec Dir Enterprise Architect

Regeneron SLEEPY HOLLOW Updated 17 September 2026
PharmaClinical ResearchRegulatory AffairsQuality Assurancegcpemacroraveinformazure

Job description

This role leads Enterprise Architecture for the organization, setting the technology vision, standards, and governance that align business strategy with scalable, secure, and future-ready technology platforms. The Executive Director partners with senior IT and business leadership to shape the enterprise technology roadmap, drive architecture decision-making across data, cloud and infrastructure, application, and integration domains, and ensure technology investments deliver measurable business value. This is both a strategic and hands-on leadership role, requiring the ability to influence at the executive level while maintaining the technical depth to guide complex, enterprise-wide architecture decisions, and to build and mentor a high-performing architecture organization. Security and AI architecture are delivered through close collaboration with the CISO and CAIO organizations, which maintain their own dedicated architecture teams; business architecture is owned by a separate business strategy function outside Digital and Technology. Where and When This is an on-site position 4 days/week, primarily based at our Sleepy Hollow, NY or Warren, NJ office. If eligible, we can offer relocation benefits; we cannot offer a fully remote option. Enterprise Architecture Strategy & Vision Define and own the enterprise architecture strategy, principles, and target-state blueprints across the data, cloud and infrastructure, application, and integration domains, incorporating security and AI architecture standards set in partnership with the CISO and CAIO organizations. Translate business strategy and digital transformation priorities into a coherent, multi-year enterprise technology roadmap. Establish and evolve the enterprise's architecture operating model, ensuring architecture decisions scale with business growth and complexity. Assess emerging technology trends (AI/ML, cloud-native platforms, automation) and determine their strategic fit and adoption path for the enterprise. Champion a “business capability first” architecture approach, ensuring technology investments map directly to business outcomes. Architecture Governance & Standards Establish and lead the enterprise architecture governance framework, including review boards, design authority processes, and exception management. Define and enforce enterprise architecture standards, patterns, and reference architectures across build, buy, and integrate decisions. Own the architecture review process for major programs and capital investments, ensuring alignment with enterprise standards, security, and regulatory requirements. Maintain the enterprise architecture repository (current-state and future-state models, technology inventories, and roadmaps) as an authoritative source of truth. Partner with Security, Risk, and Compliance to ensure architecture decisions meet enterprise risk tolerance and regulatory obligations (e.g., GxP, data privacy). Technology Roadmap & Investment Planning Lead enterprise-wide technology rationalization efforts, identifying opportunities to consolidate, retire, or modernize legacy platforms. Partner with Finance and business unit leaders to build the business case for architecture-driven investments, balancing innovation with cost discipline. Guide platform and vendor selection decisions for enterprise-critical systems, ensuring architectural fit, scalability, and total cost of ownership are fully evaluated. Own the enterprise's cloud and infrastructure strategy, ensuring architecture decisions support performance, resilience, and cost efficiency at scale. Drive the integration architecture strategy across the enterprise, enabling seamless data flow and interoperability between core business systems. Business & Digital Transformation Partnership Serve as a trusted architecture advisor to business unit leaders, translating business problems into technology-enabled solutions. Partner with product, engineering, and program leadership to embed architecture thinking early in the delivery lifecycle, reducing rework and technical debt. Lead architecture input into major digital transformation and modernization initiatives, ensuring solutions are designed for scale, security, and long-term maintainability. Evaluate and guide the adoption of AI, automation, and data platforms to accelerate business capabilities and competitive differentiation. Act as an escalation point for cross-functional architecture conflicts, driving resolution through data-driven, business-aligned decision-making. Solution & Platform Architecture Oversight Provide senior oversight and quality assurance for solution architectures developed by domain and solution architects across the enterprise. Ensure architectural consistency and reuse across programs, preventing siloed or duplicative technology investments. Guide the design of resilient, secure, and scalable platform architectures for enterprise applications, data platforms, and integration layers. Champion architecture practices that support DevOps, CI/CD, and infrastructure-as-code adoption across delivery teams. Oversee technical due diligence for mergers, acquisitions, and strategic partnerships, assessing architectural risk and integration complexity. Executive Stakeholder Engagement & Communication Present enterprise architecture strategy, roadmaps, and investment recommendations to executive leadership, technology governance forums, as needed. Build strong, trusted relationships with the Digital and Technology Leadership, and business unit executives to ensure architecture remains a strategic partner, not a bottleneck. Communicate complex technical concepts and trade-offs in clear, business-relevant terms to non-technical executive audiences. Represent the enterprise architecture function in vendor, industry, and partner forums, staying current on best practices and market direction. Establish and sustain the operating model for collaboration with the CISO and CAIO organizations' own architecture teams — defining clear decision rights, escalation paths, and shared standards so security and AI architecture decisions remain aligned to enterprise architecture without duplicated ownership. Partner with the business strategy function that owns business architecture, ensuring enterprise technology roadmaps remain traceable to business capability models maintained outside Digital and Technology. Peop

Stand out for this role

NoxPharm tailors your CV to this job description by aligning your experience with the role requirements and terminology. Built for pharma & life sciences.

Tailor my CV now — free to try