Sr. Mgr, IT - Digital Plant Applications & Infrastructure

Bristol Myers Squibb Indianapolis - RayzeBio - IN Updated 5 October 2026
PharmaBiotechRegulatory AffairsQuality Assurancegmpsasemacroinformaws

Job description

Life at BMS At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/ Job Description The Sr. Manager, IT Digital Plant Applications & Infrastructure is an integral part of bringing RayzeBio’s innovative drug products to patients in need. In this role, you will report directly to the Exec. Director, IT and be primarily responsible implementing RayzeBio’s vision for growth and leading efforts to enable digital processes to achieve commercialization objectives at the site. The role will ensure the digital systems applications along with CSV for lab and process automation are enabled and maintained to successfully deliver novel Radiopharmaceutical technologies. You will work with lab & process automation, large corporate systems, small biotech systems, across all functions for the Whitestown site. Additional responsibilities will include working with architectural and IT partners and specialty equipment manufacturers to achieve our technology and commercialization goals. Job Responsibilities Responsible for continuous operation and maintenance of IT, data for lab & process automation systems (including MES, LIMS, local manufacturing, quality control and quality management site IT systems) as well as associated site infrastructure. Key partner for Engineering and process automation space. Deliver to site service level management scope and process with IT groups and/or vendor managed services, i.e. Service Level Agreements (SLA’s), Disaster Recovery/Service Continuity, etc. Work with service providers to deliver effective, innovative and stable solutions that meet the needs of the site. Support site regulatory inspection readiness and data integrity initiatives. Partner on new demand from the various site functions (Manufacturing Operations, Quality, Supply Chain, Manufacturing Science & Technology) Identify key technology trends and how new technologies might be leveraged to provide better solutions to the manufacturing site Support deployment of long-term (3 year) roadmaps identifying capabilities that have the greatest impact on business capabilities for the organization. Partnering and benchmarking with external sources. Education and Experience: Bachelors in Engineering, IT, Science field or equivalent 7-10+ years of IT experience in biotechnology, pharmaceutical, life sciences or GxP manufacturing. Prior radiopharma experience is highly valued but not required. Proven technical leadership and management experience. Demonstrated experience implementing either automation and digitization projects. BS/MS Information Technology or similar degree or equivalent experience Skills: Ability to effectively communicate with both technical and non-technical team members. Strong interpersonal skills, especially regarding: Teamwork and collaboration Client focus Verbal and written communication Knowledge of pharma IT Architecture and IT Infrastructure including Networks, Servers, HMIs, Printers, Scanners, Switches, Firewall rules, Domains, etc. Knowledge of cGMP, GXP, GAMP, SDLC regulations, including 21CFR part 11, and good documentation practices. Knowledge of pharmaceutical, manufacturing and laboratory systems and equipment that support Biologics and clinical manufacturing. Strong technical and problem-solving skills and the ability to work independently. Demonstrated success working in a high-performing, business results-driven environment. Knowledge of Cybersecurity, patching and IT Life Cycle Management (LCM). Understanding of computer system validation. Applies AI to improve team execution and decision‑making Physical Requirements: Standard office environment coupled with GMP production and facility environment. Must be willing to wear personal protective equipment (PPE) as required. Must be comfortable working with radioactive materials. We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway. Compensation Overview: Indianapolis - RayzeBio - IN: $143,622 - $174,036
 The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guide

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