HEVA Business Partner

Job title : HEVA (HEOR) Business Partner Location: Cambridge, MA or Morristown, NJ (hybrid with 3 days a week on-site requirement) About the Job At Sanofi, we chase the miracles of science to improve people's lives. As a global pharmaceutical leader, we are committed to transforming the practice of medicine by working to turn the impossible into the possible. Our mission drives us to pursue breakthrough therapies and innovative solutions that address the world's most challenging health conditions. We believe that when we bring together diverse perspectives, cutting-edge science, and unwavering dedication to patients, we can achieve extraordinary outcomes that make a meaningful difference in the lives of millions worldwide. Sanofi's Rare franchise has a diverse and fast-growing portfolio. This includes late-stage launching candidates as well as several promising compounds in the pipeline. HEVA's mission is to conduct, communicate, and translate evidence to demonstrate the value of Sanofi's products and support optimal access and treatment outcomes for patients. HEVA Vision, Mission, and Values We are one bold HEOR team leveraging innovative HEOR to transform patient care and access. As HEOR experts, we lead the generation and dissemination of robust, business-relevant evidence to demonstrate value and drive access to medicines. The HEVA organization is driven by five core values that define how we work and deliver impact. We operate as One Team, partnering without boundaries while pursuing a Bold Purpose through ambitious, measurable goals. Grounded in Scientific Excellence with Relevance and deep technical expertise, we embrace Innovation in Action to transform how we research and deliver Impact for People, creating meaningful outcomes for patients, the healthcare ecosystem, and our colleagues who make it all possible. Join the team transforming care for people with immune challenges, rare diseases, cancers, and Specialty Care neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. About Sanofi We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Main Responsibilities This role will lead Health Economic and Outcomes Research activities for AYVAKIT® in Systemic Mastocytosis and emerging pipeline assets within the Global Rare HEVA team. Lead the development and execution of asset‑level HEOR strategies within the global HEVA framework for AYVAKIT® (avapritinib) in Systemic Mastocytosis (advanced SM and indolent SM) and assigned emerging pipeline assets, translating Target Value Propositions and access strategies into evidence hypotheses, requirements, and generation plans that address payer/provider/health system unmet needs in rare mast cell disease; operate with medium independence for strategic work and high independence for tactical execution. Design and execute HEOR research — including economic modeling, database analysis, observational research, Clinical Outcomes Assessment (COA) development and validation, systematic literature review, evidence synthesis, and value dossier development — and operationalize and execute evidence generation priorities for assigned Systemic Mastocytosis indications and emerging assets, incorporating them into broader Sanofi planning documents such as the Integrated Evidence Generation Plan (IEGP). Operate as part of a multi-functional global brand and development team responsible for designing clinical research programs to meet the evidentiary standards of regulators, HTA organizations, reimbursement authorities, and third-party payers; provide trial design recommendations; serve as a subject matter expert providing input to commercial, medical, market access, and strategy development teams; and align closely with the US HEVA team to ensure the global evidence strategy reflects US access and payer needs. Develop collaborative research relationships with payers and other decision-makers to inform value demonstration strategies for AYVAKIT® and pipeline assets, leveraging payer interactions to identify strategies that improve the impact of research and build advocates for data; support interactions with global HTA bodies and reimbursement authorities; and engage with key opinion leaders and external research partners to advance HEVA science in Systemic Mastocytosis. Contribute to scientific publications and presentations in peer-reviewed journals and at major congresses; distill complex HEOR findings into clear, audience-appropriate communications for internal and external stakeholders; maintain compliance with all relevant internal SOPs and external laws and regulations; and mentor junior colleagues on a case-by-case basis, sharing HEOR expertise and supporting their professional development. About You Advanced degree (PhD, MD, MS, MPH, or PharmD) in a scientific discipline 5 years of experience in health economics, outcomes research, or a related field Global product launch experience; understanding of payer evidence requirements and value demonstration in a competitive market Demonstrated experience applying various HEOR methods to specific research projects and supporting global launches Proficiency in principles of evidence-based medicine and clinical research methodology, economic modeling, and COAs Experience in translating Target Value Propositions and access strategies into evidence hypotheses, requirements, and generation plans Established track record of scientific and/or methods publications in peer-reviewed journals Knowledge of global HTA processes and guidelines; experience with HTA submissions preferred Strong ability to partner with colleagues from non-HEOR functional areas Compliance with all relevant internal SOPs and external laws and regulations Technical Skills: Demonstrated understanding of disease physiopathology, drug mechanism of action, health economic modeling, clinical development principles, epidemiology, biostatistics, statistical programming, COA development, systematic literature reviews, and network meta-analyses Working proficiency with HEOR-relevant digital tools and data platforms; ability to apply digital solutions to enhance research efficiency Soft Skills: Strong communication skills, both verbal and written, including presentation skills; significant experience making presentations to senior management strongly desired Understanding of the legal and regulatory environment of the pharmaceutical industry; demonstrated in