Director, COA Measurement Science

INTRODUCTORY PARAGRAPH Evinova is a health-tech business, accelerating the delivery of better health outcomes by propelling the life sciences sector forward in digital health, from the inside. Evinova delivers proven outcomes for sponsors, sites, and patients, empowering life science leaders to optimize clinical trials from start to finish. Through our application of science-based expertise, evidence-led rigour, and human experience-driven insight, our proven digital solutions are deliberately designed so that everyone can reach better health outcomes together. Evinova is a health-tech business within the AstraZeneca Group. At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person. Digital health, the point at which healthcare, technology, data and analytics converge, is the subject of great promise, with the World Health Organisation believing it has the potential to improve health for everyone. At AstraZeneca, we’ve been working hard to make this a reality, with the years of experience we have accumulated enabling us to now embed digital health at scale across R&D. To achieve our goal of improving patient experience and outcomes AstraZeneca has Digital Health as one of the top 4 strategic priorities for the company. TALK ABOUT THE SET OR BUSINESS AREA As a Director in the COA Measurement Science, Centre of Excellence you should have experience in the use of clinical outcomes assessments (COA) such as traditional survey-like instruments using rating or ranking scales and novel sensor/wearable data capture instruments to inform identification and/or evaluation of symptoms, function, health-related quality of life, or other patient-centric concepts of clinical benefit throughout the oncology drug development lifecycle. In this role, you will be responsible for providing strategic direction on qualitative and quantitative measurement expertise for the development and execution of patient-centered measurement strategies and dissemination of findings to key stakeholders, such as cross-functional teams, regulators, payers, healthcare professionals and most importantly patients in support of more efficient identification of treatment benefits vs risks. This includes but is not limited to: identification of unmet measurement need, description of context of use (e.g., selection of responders for fit-for-purpose use of Patient-Reported Outcomes, Observer-Reported Outcomes, Clinician-Reported Outcomes, or Performance Outcome assessments), definition of data collection strategy and implementation in clinical research or real world setting, collaboration for data analyses and interpretation and audience-adapted publications. As a Director, you will be expected to partner with scientific leaders within the organization to identify specific areas of interest for professional development, with the ultimate goal of becoming a recognized leader in the COA/digital health field. EXPLAIN WHAT THE ROLE INVOLVES What you’ll do As the Director, you will play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients’ lives through the following: Serve as a subject matter expert and leader in applying qualitative and quantitative research to generate evidence of patients' experience with treatment throughout the drug development lifecycle (e.g., identification of unmet measurement need, endpoints capturing symptoms, function, or quality of life evolution overtime to inform disease progression or tolerability) Contribute to qualitative and quantitative research to generate evidence of patients' experience with treatment throughout the oncology drug development lifecycle (e.g., identification and exploration of unmet measurement need, endpoints capturing symptoms, function, or quality of life evolution overtime to inform disease progression or tolerability) including study design/oversight and data collection Responsible for project management of functional service provider(s) for qualitative and quantitative research to inform development of conceptual disease-models and related endpoints to address measurement gap to inform the patients' experience with treatment. With minimal supervision, contribute to the exploration of COA in clinical research to inform clinical benefit evaluation of oncology treatment, including: measurement performance evaluation of symptom(s), function and health-related quality of life instruments, definition or development of novel COA endpoints to address evidence needs from key stakeholders, and data collection to inform decision making related to the inclusion of COA endpoints and findings in major deliverables such as: clinical development plans, study protocols, and strategic and operational reports. Prepare for regulatory filings and provide scientific input to advisory committee meetings Partner with scientific leaders within Digital Health Oncology to identify, pursue, and develop independent scientific expertise within the COA and digital health fields. Collaborate and partner with key internal stakeholder colleagues to ensure priorities and strategies are aligned, and inform the development of patient- and site-facing digital health applications. Prepare, review, and publish scientific reports, internal/ conference presentations, publications, regulatory dossiers reflecting ongoing or completed work, with minimal supervision. HIGHLIGHT THE SKILLS AND CAPABILITIES NEEDED Essential for the role Combination of academic training and practical experience in outcomes research. This may consist of: Masters degree in a related discipline , plus eight years practical experience Bachelors degree in a related discipline, plus 10 years practical experience Significant experience in performing outcomes research, in any setting, including life sciences company, research organization, academic institution or governmental agency including experience in interpreting COA data from clinical research and communicating scientific evidence. Working knowledge of Patient Focused Drug Development (PFDD) FDA Guidance documents and other relevant guidance documents and best practices to capture patient's experience in drug lifecycle, as well as experience applying this knowledge in a clinical research setting. Experience collaborating with cross-functional partners with varying levels of knowledge and experience in COA and Digital health sciences. Sufficient understanding of basic research methodologies and analytic principles that intersect with measurement science in clinical research settings (including but not limited to comparative study designs, biostatics and psychometrics), to effectively communicate, partner, and collaborate with SMEs in these fields. Experience partnering with and overseeing/mentoring junior scientists. Conceptual, analytical and strategic thinking Creative, innovative, and solution-focused Curious, embraces new ways of problem solving, new ideas, and new ways of working Strong communication skills, the ability to build relationships among cross-functional partners and stakeholders, and the ability to influence without authority. Fluent English and Mandarin, both of which must be usable as working languages Based in Shanghai or Beijing Desirable for the role Doctoral degree (e.g., Ph.D., Sc.