Head of Health, Economics & Outcomes Research (HEOR)

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases. We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients. argenx is focused on developing and commercializing product candidates with the potential to be either first-in-class against novel targets or best-in-class against known, but complex targets to treat immunologic diseases with significant unmet medical need. Changes in healthcare systems with advances in medicine and health technologies have increased the need for value-evidence to support decision making regarding the adoption of innovative therapies by various stakeholders. argenx is committed to elucidating the burden of illness faced by patients and caregivers for conditions we seek to address and providing evidence of the value of our treatments for these diseases. This will enable us to prepare for successful product launches and sustained market access to our medicines and includes generating and communicating evidence to answer questions from healthcare decision makers such as regulators, payors, Health Technology Assessment (HTA) authorities, HCPs, patient advocacy organizations, and other stakeholders in alignment with the broader strategies for our therapies. The Head, Health Economics & Outcomes Research (HEOR) leads and organizes a team of scientists and specialists to develop value-evidence supporting a large and growing portfolio. This person will collaborate with internal and external stakeholders and decision makers to lead and support the planning, design, and execution of HEOR deliverables across all phases of drug development for more than 20 pipeline and marketed indications, working with Development and Commercialization teams globally. This individual will lead the HEOR capability and collaborate cross-functionally with the other capabilities including Real World Evidence (RWE), Clinical Development, Medical Affairs & Evidence Generation (MA&EG), Market Access, Commercial, Patient Advocacy, Business Development, and Regulatory to align evidence generation efforts with identified evidence gaps. The Head, HEOR will have broad responsibility to support scientifically credible HEOR work and deliverables. This includes partnering with external clinical and research experts and patient advocates. The individual will be expected to understand and engage with colleagues across the organization to provide the necessary insights to guide value-evidence needs for molecules in development and value-evidence possibilities for commercialized products aligned with defined strategy. Importantly, the Head of HEOR is responsible for developing the strategy for capability excellence at argenx, not only in the short-term but also for the long-term considering the evolving technology environment, expanding portfolio, and access landscape globally. This includes cross-functional collaboration to effectively define capability scope, budget and timelines to support a team that produces and disseminates relevant, targeted, and timely value evidence across argenx markets and for given conditions of interest. Additionally, this individual is a member of the MA&EG Leadership Team and co-owns achievement of the MA&EG vision at argenx and excellence of the MA&EG Community in achieving our goals. Roles and Responsibilities: Lead, align, and maintain HEOR evidence generation plans with RWE, Clinical Development, Regulatory, MA&EG, Market Access, and Commercialization demonstrating unmet patient need and the value of argenx treatments inmultiple markets. These plans should be aligned with indication/molecule strategies and incorporated into the integrated evidence generation plans for the given indication/molecule in collaboration with MA&EG and data communication plans in collaboration with Scientific Communications. Lead and mentor a team of HEOR scientists who develop strategic value evidence generation plans and execute them including the conduct and timing of analyses, timelines, and budget management. Working with internal stakeholders and external experts, develop impactful value-evidence generation plans and on time deliverables. Lead HEOR organizational evolution to meet the needs of a growing commercialization organization with the anticipation of several new indication/molecule launches in multiple markets over the next few years, requiring close partnership with Market Access and Commercial to meet their needs. This will also require ongoing reduction of administrative burden and prioritization. Partner closely with Market Access to align on local market evidence generation needs and key priorities for execution including their timely and coordinated delivery. Support the team of HEOR Scientists to collaborate with argenx stakeholders broadly to identify, select, and execute value-evidence projects with consideration for Health Care Practitioner (HCP) and patient advocacy integration, regulatory concerns, legal, and compliance. Lead HEOR connecting with the internal and external community to keep abreast of developments in the environment impacting stakeholder needs to direct value-evidence planning. Lead broad evidence dissemination through high-quality publications in collaboration with investigators, HCPs/KOLs, and patient advocates as appropriate that will contribute to company discussions with and submissions to payers/HTAs. Partner closely with argenx MA&EG, RWE, and Patient Advocacy to identify, enlist, and maintain the interest of HCPs/KOLs and Patient Advocacy Groups relevant to the disease states being studied to inform our work and/or partner on its execution. Contribute as a member of the MA&EG Leadership Team to drive the broader Community to deliver on its vision and support people development. Participate as a member of the argenx government relations community, executing relevant evidence generation in support of our strategies. Upon request, and in partnership with field Market Access and MA&EG, develop and deliver presentations to external stakeholders. Conduct internal training on HEOR to educate argenx colleagues on the importance of value-evidence and the unique challenges in developing and executing these projects. Skills and Competencies: Technical Mastery: Has a thorough understanding and expertise across HEOR areas and experience supporting markets worldwide. Knowledge of and experienced in different types of HEOR studies, e.g. cost effectiveness, cost-utility, cost-benefit, and budget impact modeling, literature reviews and syntheses, comparative effectiveness research, observational noninterventional studies, prospective cohort studies, etc. Leadership: Experience building and developing teams and individuals. Can develop others who are in different stages of their careers to produce successful outcomes and grow skills. Able to reflect on one’s own strengths and development area